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$100.00
Amino Acid Sequence:
While NAD+ is not a peptide, consists of an adenine ring, two ribose sugar moieties, phosphate groups, and a nicotinamide ring. It is synthesized in the body from the amino acid tryptophan, nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN).
Chemical Formula:
C₂₁H₂₇N₇O₁₄P₂
CAS Registry Number:
53-84-9
Mitochondrial function & energy metabolism
Healthy aging & longevity pathways
DNA repair & genomic stability
Neuroprotection & cognitive support
Metabolic flexibility & insulin sensitivity
Oxidative‑stress and inflammation modulation
Cardiometabolic health & cellular resilience
Mitochondrial Energy Production
Essential cofactor in oxidative phosphorylation
Supports ATP generation through electron‑transport chain activity
Maintains redox balance (NAD+/NADH ratio)
Sirtuin Activation & Longevity Pathways
Activates sirtuins (SIRT1–SIRT7) involved in DNA repair
Supports genomic stability and cellular stress resistance
Influences metabolic and circadian regulation
DNA Repair & Cellular Protection
Required for PARP‑mediated DNA repair
Supports cellular recovery from oxidative stress
Enhances mitochondrial biogenesis and turnover
Metabolic Regulation
Improves metabolic flexibility
Supports glucose and lipid metabolism
Influences inflammatory and oxidative‑stress pathways
NAD+ is an experimental research compound and is not FDA‑approved for therapeutic use. Current evidence is derived from preclinical studies and early‑stage human investigations. Despite its investigational status, NAD+ remains a leading molecule of interest in longevity science, mitochondrial research, and metabolic‑health studies due to its central role in cellular energy and repair pathways.
1. Covarrubias AJ, Perrone R, Grozio A, Verdin E. NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021 Feb;22(2):119-141.
2. Imai S, Guarente L. NAD+ and sirtuins in aging and disease. Trends Cell Biol. 2014 Aug;24(8):464-71.
3. Rajman L, Chwalek K, Sinclair DA. Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence. Cell Metab. 2018 Mar 6;27(3):529-547.
4. Zapata-Pérez R, Wanders RJA, van Karnebeek CDM, Houtkooper RH. NAD+ homeostasis in human health and disease. EMBO Mol Med. 2021 Jul 7;13(7):e13943.
5. Lautrup S, Hou Y, Fang EF, Bohr VA. Roles of NAD+ in Health and Aging. Cold Spring Harb Perspect Med. 2024 Jan 2;14(1):a041193.
6. Amjad S, Nisar S, Bhat AA, Shah AR, Frenneaux MP, Fakhro K, Haris M, Reddy R, Patay Z, Baur J, Bagga P. Role of NAD+ in regulating cellular and metabolic signaling pathways. Mol Metab. 2021 Jul;49:101195.
7. Reiten OK, Wilvang MA, Mitchell SJ, Hu Z, Fang EF. Preclinical and clinical evidence of NAD+ precursors in health, disease, and ageing. Mech Ageing Dev. 2021 Oct;199:111567.
CURRENT BATCH LOT NUMBER: N7502026-06-05
CERTIFICATE OF ANALYSIS – TGMPURE NAD+ 500 MG (N7502026-06-05)
Nicotinamide Adenine Dinucleotide (NAD+) is a naturally occurring coenzyme found in every cell of the body, essential for energy production, mitochondrial function, and cellular repair. As a central component of metabolic pathways, NAD+ supports ATP generation, redox balance, and the activity of sirtuins—key regulators of longevity, DNA integrity, and cellular resilience.
Research interest in NAD+ has grown significantly due to its role in healthy aging, metabolic efficiency, neuroprotection, and cellular stress response. NAD+ levels naturally decline with age, and modern studies explore how restoring NAD+ availability may support mitochondrial performance, metabolic flexibility, and overall cellular vitality. Its involvement in DNA repair, oxidative‑stress defense, and energy metabolism has made NAD+ a leading molecule in longevity and cellular‑health research.
QUANTITY: 500 MG
