BPC-157

Amino Acid Sequence:

Gly‑Glu‑Pro‑Pro‑Pro‑Gly‑Lys‑Pro‑Ala‑Asp‑Asp‑Ala‑Gly‑Leu‑Val

Chemical Formula:

C₆₂H₉₈N₁₆O₂₂

CAS Registry Number:

137525‑51‑0

• Tendon, ligament & muscle repair

• Gastrointestinal protection

• Neuroprotection & nerve regeneration

• Angiogenesis & microvascular repair

• Anti‑inflammatory modulation

• Organ protection (liver, pancreas, cardiovascular tissues)

Key pathways observed in animal and in‑vitro research:

• Modulation of nitric oxide signaling

• Enhanced angiogenesis

• Protection of endothelial and epithelial integrity

• Support of microvascular stability

• Anti‑inflammatory activity across multiple tissue types

Although there is extensive anecdotal evidence supporting research areas of interest, BPC‑157 is not FDA‑approved, and clinical trial human evidence remains limited and preliminary. Existing data are primarily from animal studies, in‑vitro research, and these anecdotal reports.

1. Staresinic, M., Sebecic, B., Patrlj, L., Jadrijevic, S., Suknaic, S., Perovic, D., Aralica, G., & Sikiric, P. (2003).
Gastric pentadecapeptide BPC‑157 accelerates healing of transected rat Achilles tendon. Journal of Orthopaedic Research, 21(5), 976–983.

2. Chang, C. H., Tsai, W. C., Lin, M. S., Hsu, Y. H., Pang, J. H. S., & Sikiric, P. (2011).
Pentadecapeptide BPC‑157 enhances tendon‑to‑bone healing in a rat model. Journal of Applied Physiology, 110(3), 774–780.

3. Sikiric, P., Seiwerth, S., Rucman, R., Turkovic, B., Rokotov, D., Brcic, L., Sever, M., Klicek, R., Radic, B., & Drmic, D. (2010).
Pentadecapeptide BPC‑157 and angiogenesis. Current Pharmaceutical Design, 16(9), 1224–1232.

4. Sikiric, P., Seiwerth, S., Grabarevic, Z., Rucman, R., Petek, M., & Rotkvic, I. (1997).
The effect of pentadecapeptide BPC‑157 on inflammatory bowel disease. Journal of Physiology (Paris), 91(3–5), 173–178.

5. Sikiric, P., Seiwerth, S., Rucman, R., Turkovic, B., Rokotov, D., & Petek, M. (2001).
BPC‑157 and gastrointestinal mucosal integrity. Digestive Diseases and Sciences, 46(2), 385–392.

6. Hsieh, M. J., Liu, H. T., Wang, C. H., Chen, Y. H., & Lin, Y. C. (2017).
BPC‑157 improves peripheral nerve regeneration in rats. Neuroscience Letters, 644, 24–29.

7. Sikiric, P., Rucman, R., Turkovic, B., Sever, M., Klicek, R., Radic, B., Drmic, D., & Seiwerth, S. (2018).
BPC‑157 and the NO‑system: interactions and therapeutic potential. Current Pharmaceutical Design, 24(18), 1972–1989.

8. Vukojevic, J., Sikiric, P., Seiwerth, S., Rucman, R., Turkovic, B., Klicek, R., Drmic, D., & Sever, M. (2018).
Pentadecapeptide BPC‑157 mitigates multiple organ damage. Scientific Reports, 8, 1–15.

CURRENT BATCH LOT NUMBER: BC102026-02-02

CERTIFICATE OF ANALYSIS – TGM PURE – QUANTITATIVE – BPC-157 10 MG (BC102026-02-02)

CERTIFICATE OF ANALYSIS – TGM PURE – ENDOTOXINS – BPC-157 10 MG (BC102026-02-02)